Post by shahadat560 on Jan 18, 2024 4:27:49 GMT -5
It was the first drug used in Covid-19 patients to make newspaper headlines . Hydroxychloroquine , the active ingredient in drugs against malaria , lupus or rheumatoid arthritis, is actually very old. It was used in Peru in the 17th century against fever and chills and, soon, against malaria. Now, in this pandemic, it seemed to have found new life .
It began to be administered in patients admitted for infection caused by SARS-CoV-2 in combination with other drugs (also in Spain and also in Lugo) and clinical trials began with it for this specific use . There are currently about 150 in operation. When cases were multiplying in the United States, its president called it "the miracle drug", to the horror Country Email List of the entire scientific community for attributing properties to it that had not yet been proven . He also said that he took it preventively and, after that announcement, the news of the death of an Arizona man who drank the aquarium cleaner he had at home and that contained chloroquine phosphate went around the world .
On May 22, the prestigious scientific journal The Lancetpublished a devastating study , with immediate consequences. It concluded that, far from improving the prognosis of patients with Covid-19, hydroxychloroquine actually increased their mortality . The World Health Organization immediately stopped the section of its Solidarity mega-study that was dedicated to evaluating the effectiveness of that drug. Many countries did the same with their trials underway . Not Spain. Here they continued ahead, although they were forced to analyze their safety and no problems were found.
The study published in The Lancet, now withdrawn, caused the WHO to stop a mega clinical trial on the effectiveness of the drug
In the scientific community there were those who received this publication with raised eyebrows. Among them, the Vilabé epidemiologist from IS Global in Barcelona, Alberto García Basteiro . He explains that, in reality, the first alert was that of his colleague Carlos Chaccour . "He is a world expert in ivermectin , an antiparasitic drug whose potential against malaria is being analyzed," he says. Up to date with all the news about this drug, Chaccour read a preprint (an unreviewed publication) that attributed an 80% decrease in mortality to Covid-19 patients treated with it. He wrote to the authors to ask several details about the database they had used and they responded "evasive," says García Basteiro. That preprint had immediate repercussions . Peru established protocols for the use of ivermectin in all coronavirus patients. "Since there was not enough stock , we even used the veterinary service...", he explains.
It began to be administered in patients admitted for infection caused by SARS-CoV-2 in combination with other drugs (also in Spain and also in Lugo) and clinical trials began with it for this specific use . There are currently about 150 in operation. When cases were multiplying in the United States, its president called it "the miracle drug", to the horror Country Email List of the entire scientific community for attributing properties to it that had not yet been proven . He also said that he took it preventively and, after that announcement, the news of the death of an Arizona man who drank the aquarium cleaner he had at home and that contained chloroquine phosphate went around the world .
On May 22, the prestigious scientific journal The Lancetpublished a devastating study , with immediate consequences. It concluded that, far from improving the prognosis of patients with Covid-19, hydroxychloroquine actually increased their mortality . The World Health Organization immediately stopped the section of its Solidarity mega-study that was dedicated to evaluating the effectiveness of that drug. Many countries did the same with their trials underway . Not Spain. Here they continued ahead, although they were forced to analyze their safety and no problems were found.
The study published in The Lancet, now withdrawn, caused the WHO to stop a mega clinical trial on the effectiveness of the drug
In the scientific community there were those who received this publication with raised eyebrows. Among them, the Vilabé epidemiologist from IS Global in Barcelona, Alberto García Basteiro . He explains that, in reality, the first alert was that of his colleague Carlos Chaccour . "He is a world expert in ivermectin , an antiparasitic drug whose potential against malaria is being analyzed," he says. Up to date with all the news about this drug, Chaccour read a preprint (an unreviewed publication) that attributed an 80% decrease in mortality to Covid-19 patients treated with it. He wrote to the authors to ask several details about the database they had used and they responded "evasive," says García Basteiro. That preprint had immediate repercussions . Peru established protocols for the use of ivermectin in all coronavirus patients. "Since there was not enough stock , we even used the veterinary service...", he explains.